Breast Cancer Remotely Imposes a Myeloid Bias on Haematopoietic Stem Cells by Reprogramming the Bone Marrow Niche

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Using unbiased transcriptomic analysis and in situ imaging of HSCs and the bone marrow niche during breast cancer, researchers showed that both HSCs and mesenchymal stem cells were transcriptionally and spatially modified.
[Nature Cell Biology]
Abstract