Enhanced CD19 Activity in B Cells Contributes to Immunodeficiency in Mice Deficient in the ICF Syndrome Gene Zbtb24

0
114
Investigators showed that mice deficient in Zbtb24 in the hematopoietic lineage recapitulated the major clinical features of patients with immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome.
[Cellular & Molecular Immunology]
Abstract