Engineered Mesenchymal Stem Cell-Derived Small Extracellular Vesicles for Diabetic Retinopathy Therapy Through HIF-1α/EZH2/PGC-1α Pathway

Scientists presented evidence that the intravitreal injection of MSC-small extracellular vesicles improved retinal function and alleviated retinal apoptosis, inflammation, and angiogenesis in both db/db mice and streptozotocin-induced diabetic rats.