CCT2 Prevented β-Catenin Proteasomal Degradation to Sustain Cancer Stem Cell Traits and Promote Tumor Progression in Epithelial Ovarian Cancer

Chaperonin containing TCP1 subunit 2 (CCT2) expression and prognostic value in epithelial ovarian cancer samples were assessed according to TCGA dataset. CSC traits were evaluated by RT-PCR, WB assays, sphere-forming assays and chemoresistance analysis.