N⁶ Methyladenosine Eraser FTO Suppresses Staphylococcus aureus-Induced Ferroptosis of Bone Marrow Mesenchymal Stem Cells to Ameliorate Osteomyelitis Through Regulating the MDM2/TLR4/SLC7A11 Signaling Pathway

Investigators found that Staphylococcus aureus treatment promoted the accumulation of iron, Fe2+, lipid peroxide, and malondialdehyde, increased TFRC and reduced FTH1 and GPX4 to trigger ferroptosis in rat bone marrow mesenchymal stem cells.