HLA-DPA1*02:01~B1*01:01 Is a Risk Haplotype for Primary Sclerosing Cholangitis Mediating Activation of NKp44+ NK Cells

NK cell activation on NKp44/HLA-DP interactions was assessed in vitro using plate-bound HLA-DP molecules and HLA-DPB wildtype versus knock-out human cholangiocyte organoids.