Alcohol and E-Cigarette Damage Alveolar-Epithelial Barrier by Activation of P2X7r and Provoke Brain Endothelial Injury via Extracellular Vesicles

Investigators used a model of primary human pulmonary alveolar epithelial cells and exposed the cells to 100 mM ethanol, 100 µM acetaldehyde, or e-Cig conditioned media, and measured the mitochondrial efficiency using Agilent Seahorse machine.