Macrophages Reprogramming Improves Immunotherapy of IL-33 in Peritoneal Metastasis of Gastric Cancer

In immunocompetent mice, intraperitoneal administration of IL-33 could induce a celiac inflammatory environment, activated immunologic effector cells, and reverse the immunosuppressive tumor microenvironment, which effectively delayed tumor progression and peritoneal metastasis of gastric cancer.