Sequential Gene Expression Analysis of Myelodysplastic Syndrome Transformation Identifies HOXB3 and HOXB7 As the Novel Targets for Mesenchymal Cells in Disease

Researchers described sequential molecular changes and identified biomarkers in MSC of myelodysplastic syndrome (MDS) transformation. MDS-MSC was further isolated and cultured in vitro to determine the potential diagnostic and prognostic value of the identified biomarkers.