Immortalised Chronic Myeloid Leukemia (CML) Derived Mesenchymal Stromal Cells (MSC) Line Retains the Immunomodulatory and Chemoprotective Properties of CML Patient-Derived MSCs

Researchers generated and characterized an immortalized chronic myeloid leukemia (CML) patient-derived MSC line and assessed its role in leukemic stem cell maintenance. They also compared the immunophenotype and differentiation potential between primary CML MSCs at diagnosis, post-treatment, and normal bone marrow MSCs.