Lucanthone, a Potential PPT1 inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation and Slows the Growth of Temozolomide-Resistant Gliomas In Vivo

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The authors reported that the anti-schistosome agent lucanthone impeded tumor growth in a preclinical model of temozolomide-resistant glioblastoma, and reduced the numbers of stem-like glioma cells.
[Journal of Pharmacology and Experimental Therapeutics]
Abstract