Lucanthone, a Potential PPT1 inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation and Slows the Growth of Temozolomide-Resistant Gliomas In Vivo

The authors reported that the anti-schistosome agent lucanthone impeded tumor growth in a preclinical model of temozolomide-resistant glioblastoma, and reduced the numbers of stem-like glioma cells.