Statins Affect Human iPSC-Derived Cardiomyocytes by Interfering with Mitochondrial Function and Intracellular Acidification

Scientists investigated the effects of statins on human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-derived CMs). hiPSC-derived CMs were exposed to simvastatin, atorvastatin, rosuvastatin, and cerivastatin at increasing concentrations.