PARD3 Drives Tumorigenesis through Activating Sonic Hedgehog Signaling in Tumor-Initiating Cells in Liver Cancer

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The essential role of Par-3 Family Cell Polarity Regulator (PARD3) in mediating hepatic tumorigenesis was assessed in diet-induced spontaneous liver tumor and syngeneic tumor models.
[Journal of Experimental & Clinical Cancer Research]
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