Delivery of Interferon β-Encoding Plasmid via Lipid Nanoparticle Restores Interferon β Expression to Enhance Antitumor Immunity in Colon Cancer

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Researchers tested the hypothesis that cationic lipid nanoparticle delivery of interferon β (IFNβ)-encoding plasmid to tumors was effective in restoring IFNβ expression to suppress tumor immune evasion.
[ACS Nano]
AbstractGraphical Abstract