NewslettersDermal Cell NewsDifferential Histone Acetylation and Super-Enhancer Regulation Underlie Melanoma Cell DedifferentiationBy Laurisa Dohm - February 12, 2024072Scientists identified ITGA3 gene as marked by a super-enhancer element in the Epgn3 invasive cells. Silencing of ITGA3 enhanced invasiveness in both in vitro and in vivo systems suggesting it as a negative regulator of invasion.[JCI Insight]Abstract