Human Induced Pluripotent Stem Cells Are Resistant to Human Cytomegalovirus Infection Primarily at the Attachment Level Due to the Reduced Expression of Cell-Surface Heparan Sulfate

Scientists compared the susceptibility of neonatal human dermal fibroblast cells and human hiPSCs derived from neonatal human dermal fibroblast cells, which were genetically identical to human cytomegalovirus, using immunostaining, microarray, in situ hybridization, quantitative PCR, and scanning electron microscopy.