SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cells Migration to Epidermis through p53/SCF/C-KIT Signaling

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Scientists demonstrated that after SPRY1 knockout in epidermal keratinocytes, melanocyte stem cells in the hair follicle exit the niche without depleting the pool of these cells.
[Journal Of Investigative Dermatology]
AbstractGraphical Abstract