H2AK119ub1 Differentially Fine-Tunes Gene Expression by Modulating Canonical PRC1- and H1-Dependent Chromatin Compaction

Researchers revealed that H2AK119ub1 had two distinct roles in gene expression, through differentially modulating chromatin compaction mediated by canonical polycomb repressive complex 1 (PRC1) and the linker histone H1.