NewslettersESC & iPSC NewsPRODH Safeguards Human Naive Pluripotency by Limiting Mitochondrial Oxidative Phosphorylation and Reactive Oxygen Species ProductionBy Noshin Noorjahan - March 14, 2024024Investigators reported that, proline dehydrogenase (PRODH), a mitochondria-localized proline metabolism enzyme, was dramatically upregulated in naive hESCs compared to their primed counterparts.[EMBO Reports]Full ArticleGraphical Abstract