Inhibition of miR-25 Ameliorates Cardiac and Skeletal Muscle Dysfunction in Aged mdx/utrn Haploinsufficient (+/-) Mice

Scientists created a gene transfer using a miR-25 Tough Decoy RNAs inhibitor delivered via recombinant adeno-associated virus serotype 9 to evaluate the effect of miR-25 inhibition on cardiac and skeletal muscle function in aged dystrophin/utrophin haploinsufficient mice mdx/utrn (+/-).