The Alanyl-tRNA Synthetase AARS1 Moonlights as a Lactyl-Transferase To Promote YAP Signaling in Gastric Cancer

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Alanyl-tRNA synthetase 1 (AARS1) was identified as a Hippo target gene that formed a positive feedback loop with YAP-TEAD to promote gastric cancer cell proliferation.
[Journal Of Clinical Investigation]
AbstractGraphical Abstract