Stimulatory Effect of Methylglyoxal on Capsaicin-Sensitive Lung Vagal Afferents in Rats: Role of TRPA1

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Scientists showed that intravenous injection of methylglyoxal in anesthetized, spontaneously breathing rats elicited pulmonary chemoreflexes characterized by apnea, bradycardia, and hypotension.
[American Journal Of Physiology-Regulatory Integrative And Comparative Physiology]
Abstract