CircHAS2 Activates CCNE2 to Promote Cell Proliferation and Sensitizes the Response of Colorectal Cancer to Anlotinib

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Investigators sought to determine the potential functions and specific mechanisms of circHAS2 in colorectal cancer progression and its role in predicting clinical response to anlotinib. CircHAS2 was a potent biomarker predictive of anlotinib sensitivity, both in patient-derived organoids and xenograft models.
[Molecular Cancer]
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