Precision Delivery of Human Bone Marrow-Derived Mesenchymal Stem Cells into the Pancreas Via Intra-arterial Injection Prevents the Onset of Diabetes

Using a mouse model, in which repetitive low doses of STZ induced a gentle, but progressive, hyperglycemia, investigators tested bone marrow-derived MSCs which were shown to be enriched with pro-angiogenic and immunomodulatory factors.