MST1/2 Regulates Fibro/Adipogenic Progenitor Fate Decisions in Skeletal Muscle Regeneration

Using inducible conditional knockout mice, the authors showed that blocking mammalian Ste20-like kinases 1/2 (MST1/2) of fibroblast/adipose progenitors prevented apoptosis and reduced interleukin-6 secretion in vivo and in vitro.