Yin Yang 1 Regulates Cohesin Complex Protein SMC3 in Mouse Hematopoietic Stem Cells

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Researchers found that Yin Yang 1 (YY1) physically interacted with structural maintenance of chromosomes 3 (SMC3) and co-occupied with SMC3 at a large cohort of promoters genome-wide, and YY1 deficiency deregulated the genetic network governing cell metabolism.
[Blood Advances]
Abstract