RCHY1 and OPTN Are Required for Melanophagy, Selective Autophagy of Melanosomes

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Scientists proposed that the β-mangostin-mediated melanin degradation mechanism is melanophagy, selective autophagy of melanosomes, and that autophagy receptor optineurin (OPTN) and an E3-ligase RCHY1 were required for this process.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Abstract