A Novel Long Non-Coding RNA SLNCR1 Promotes Proliferation, Migration, and Invasion of Melanoma via Transcriptionally Regulating SOX5

Researchers showed that steroid receptor RNA activator-like non-coding RNA (SLNCR1) was significantly up-regulated in human malignant melanoma tissues and cell lines and functioned as an oncogene. Silencing of SLNCR1 suppressed melanoma cell proliferation, migration, invasion, and inhibited tumorigenesis in a mouse xenograft model.