The Hepatokine FGL1 Regulates Hepcidin and Iron Metabolism during Anemia in Mice by Antagonizing BMP Signaling

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Scientists identified the hepatokine fibrinogen-like 1 (FGL1) as a previously undescribed suppressor of hepcidin that was induced in the liver in response to hypoxia during the recovery from anemia, and in thalassemic mice.
[Blood]
Abstract