KLF15 Maintains Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Thoracic Aortic Dissection by Interacting with MRTFB

Investigators explored unknown aspects of Krüppel-like factor 15 (KLF15) function. They found that KLF15 expression was reduced in human thoracic aortic dissection (TAD) samples and β-aminopropionitrile monofumarate (BAPN)-induced TAD mouse model.