Compensatory Growth and Recovery of Cartilage Cytoarchitecture after Transient Cell Death in Fetal Mouse Limbs

Investigators showed that transient sparse cell death in the mouse fetal cartilage was repaired postnatally, via a two-step process. During injury, progression of chondroprogenitors towards more differentiated states is delayed, leading to altered cartilage cytoarchitecture and impaired bone growth.