Arterial Smooth Muscle Cell AKAP150 Mediates Exercise-Induced Repression of Ca_V1.2 Channel Function in Cerebral Arteries of Hypertensive Rats

Spontaneously hypertensive rats and newly generated smooth muscle–specific AKAP150 knockin mice were used to assess the role of myocyte AKAP150/CaV1.2 channel in regulating cerebral artery function after exercise intervention.