Tailored Apoptotic Vesicles Promote Bone Regeneration by Releasing the Osteoinductive Brake

Researchers compared MSCs, MSC derived apoptotic vesicles (MSC-apoVs), and MSC-exosomes from two types of MSC. They generated a map of miRNAs specific to MSC-apoVs and identified seven miRNAs specifically enriched in MSC-apoVs compared to MSCs and MSC-exosomes.