NewslettersHematopoiesis NewsPyrimidine Depletion Enhances Targeted and Immune Therapy Combinations in Acute Myeloid LeukemiaBy Noshin Noorjahan - April 24, 2024023Researchers introduced HOSU-53, a dihydroorotate dehydrogenase inhibitor with significant monotherapy activity, which was further enhanced when combined with other standard-of-care therapeutics.[JCI Insight]Full Article