Heparan Sulfate Chain-Conjugated Laminin-E8 Fragments Advance Paraxial Mesodermal Differentiation Followed by High Myogenic Induction from hiPSCs

A system was described for differentiating hiPSCs on new generation laminin fragments, a recombinant form of a laminin E8 fragment conjugated to the heparan sulfate chains attachment domain of perlecan.