Allergen-Encapsulating Nanoparticles Reprogram Pathogenic Allergen-Specific Th2 Cells to Suppress Food Allergy

Scientists investigated the ability of allergen-encapsulating nanoparticles (NPs) to directly suppress pathogenic Th2 responses and reactivity in a mouse model of food allergy. NPs associated with pro-tolerogenic antigen-presenting cells, provoking the accumulation of suppressive regulatory T cells in the small intestine lamina propria.