Aberrant Activation of TGF-β/ROCK1 Enhances Stemness during Prostatic Stromal Hyperplasia

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Investigators demonstrated that the aberrant activation of transforming growth factor β (TGF-β)/Rho kinase 1 (ROCK1) increased the stemness of benign prostatic hyperplasia (BPH) tissue by recruiting mesenchymal stem cells, indicating the important role of embryonic reawakening in BPH.
[Cell Communication and Signaling]
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