Inhibition of Caspase Pathways Limits CD4+ T Cell Loss and Restores Host Anti-Retroviral Function in HIV-1 Infected Humanized Mice With Augmented Lymphoid Tissue

Researchers utilized exogenous injection of the human recombinant FMS-like tyrosine kinase 3 ligand into the hematopoietic stem cell cord blood human immune system mouse model to significantly expand the total area of lymph node and the number of circulating human T cells.