ISWI Chromatin Remodeling Complexes Recruit NSD2 and H3K36me2 in Pericentromeric Heterochromatin

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Investigators revealed the mechanism of heterochromatin targeting of histone H3 lysine36 dimethylation (H3K36me2). Among several H3K36 methyltransferases, NSD2 was responsible for inducing heterochromatic H3K36me2.
[Journal of Cell Biology]
Abstract