Fusobacterium nucleatum Infection Modulates the Transcriptome and Epigenome of HCT116 Colorectal Cancer Cells in an Oxygen-Dependent Manner

Using a multiomic approach, researchers analyzed epigenomic alterations of H3K27ac and global transcriptomic alterations sustained within a hypoxia and normoxia conditioned colorectal cancer cell line at 24 h following initial infection with F. nucleatum.