Brain Delivery of Protein Therapeutics by Cell Matrix-inspired Biomimetic Nanocarrier

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Inspired by the natural environment of active proteins, scientists used the cell matrix components hyaluronic acid and protamine to self-assemble with proteins to form a protein-loaded biomimetic core and then incorporated it into ApoE3-reconstituted high-density lipoprotein to form a protein-loaded biomimetic nanocarrier.
[Advanced Materials]
Abstract