Cetuximab Inhibits Colorectal Cancer Development through Inactivating the Wnt/β-Catenin Pathway and Modulating PLCB3 Expression

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Scientists investigated the influence of PLCB3, a potential colorectal cancer (CRC) oncogene, on cetuximab treatment. In vitro tests revealed that cetuximab exerted a cytotoxic effect on CRC cells, with PLCB3 knockdown inhibiting CRC cell progression.
[Scientific Reports]
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