IL1β-NFκβ-Myocardin Signaling Axis Governs Trophoblast-Directed Plasticity of Vascular Smooth Muscle Cells

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Analysis of genetic markers on E13.5, E16.5, and E19.5 in the rat metrial gland, the entry point of uterine arteries, revealed that trophoblast invasion was associated with downregulation of MYOCARDIN, α-smooth muscle actin, and calponin1, and concomitant upregulation of Smemb in vascular smooth muscle cells.
[FASEB Journal]
Abstract