Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology

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Challenges both specific, e.g. the lack of specific markers to thoroughly validate human induced pluripotent stem cell-smooth muscle cells (hiPSC-SMC), and general, e.g. a lack of transparency and consensus around methodology in the field, remain. Scientists highlight the recent successes and remaining challenges of the hiPSC-SMC model.
[Arteriosclerosis Thrombosis And Vascular Biology]
Abstract