Inhibition of TBL1 Cleavage Alleviates Doxorubicin-Induced Cardiomyocytes Death by Regulating the Wnt/β-Catenin Signal Pathway

Researchers observed a reduction in transducin beta-like protein 1 (TBL1) protein expression levels as well as cleavage events in the transplanted cardiac tissues of patients diagnosed with dilated cardiomyopathy and doxorubicin-induced cardiotoxicity.
[Cardiovascular Research]
AbstractGraphical Abstract