TIF1β Activates Leukemic Transcriptional Program in HSCs and Promotes BCR::ABL1-Induced Myeloid Leukemia

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Scientists generated a BCR::ABL1 conditional knock-in (KI) mouse model, which developed aggressive myeloid leukemia, and demonstrated that the deletion of the Tif1β gene inhibited the progression of myeloid leukemia and showed longer survival than that in BCR::ABL1 KI mice
[Leukemia]
Abstract