TCF7L1 Regulates Colorectal Cancer Cell Migration by Repressing GAS1 Expression

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By silencing and overexpressing TCF7L1 in colorectal cancer (CRC) cell lines, investigators demonstrated that TCF7L1 promoted migration, invasion, and adhesion. They demonstrated that GAS1 was a critical mediator of TCF7L1-dependent CRC cell migratory phenotypes.
[Scientific Reports]
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