Azathioprine Promotes Intestinal Epithelial Cell Differentiation into Paneth Cells and Alleviates Ileal Crohn’s Disease Severity

Upon in vitro azathioprine stimulation, intestinal epithelial cell line MODE-K exhibited heightened expression levels of paneth cell marker in concert with diminished cell proliferation but boosted mitochondrial oxidative phosphorylation activity.
[Scientific Reports]
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