Inulin-Gel-Based Oral Immunotherapy Remodels the Small Intestinal Microbiome and Suppresses Food Allergy

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Scientists reported an inulin gel formulated with an allergen that normalized the dysregulated ileal microbiota and metabolites in allergic mice, establishes allergen-specific oral tolerance and achieved robust oral immunotherapy efficacy with sustained unresponsiveness in food allergy models.
[Nature Materials]
Abstract