Salivary Gland Organoid Transplantation as a Therapeutic Option for Radiation-Induced Xerostomia

Human salivary gland stem cells were isolated from the salivary gland tissues and cultured in both Matrigel and collagen. Investigators compared the gene and protein expression patterns of salivary gland–specific markers and measured amylase activity in the two types of human salivary gland organoids.